The game features both competitive and cooperative modes. In both modes, Villains do not go into a player's deck when defeated, but instead grant a one-time reward. In competitive play, defeated Villains give players victory points, then go under their superhero cards.
The main way to play is the Co-op Campaign: 8 Scenarios, each in a resealable packet. Character progression and record-keeping offers legacy style play, but without any permanent changes. Replayable! Solo Mode! And more!